That's if you wanted them to live on the surface, which seems to be a pretty tough problem to solve in any fashion. If we're contemplating living in the clouds, maybe a lifeform more birdlike or gasbag-jellyfish-like would make sense.
Granted, I'm not sure I would want to show up to a blind date with a human/portuguese man-o-war hybrid.
Plus ATP, the cell-internal energy distribution mechanism that is a property of all life on earth destroys itself at 52 degrees celcius. That means no controlled energy actions can happen in cells above 52 degrees celcius. We'd have to redesign every enzyme, every single cell function.
I am confused about your point. The original statement was "ATP, the cell-internal energy distribution mechanism that is a property of all life on earth destroys itself at 52 degrees celcius". I pointed out that thermophilic bacteria exists and reproduce at over 52 C. Therefore, there's an apparent contradiction.
Is your statement about "roll differently" mean that there is no ATP synthesis? Certainly not, as your link shows. Is your statement that thermophilic bacteria isn't alive? I strongly doubt it. What then does it mean to "roll differently" in the context of ATP presence being a requirement for all life on earth, and hence a 52C upper limit?
So step 1 in venusforming humans is to create a non-DNA-based life form. That might take a while.