But it doesn't combine with ops. You'd need to talk about a hecatops or a hecatontops. And even more than it can't combine with ops, it can't combine with clops because there is no such root.
Sure, it does, in English, which stole prefixes, suffixes, and roots from Latin, Greek, and many other languages, and has no problem using them together, without special concern about where it got them from.