Eh... I know someone that hates opiates including heroin, they just made them feel sick and want to sleep it off. Some people though do one hit and that is forever after their jam.
I know some people that don't like cocaine, it makes them feel jittery and uncomfortable at best. Some people take a hit of coke and it takes over their whole night and that's all they want to do for the rest of the night. I was never impressed.
Nictoine, arguably one of the most addictive substances ever, has always been one of my least favorite substances (to the point of being substantially less preferable than abstaining) despite constant exposure to it in my 20's from my friends. I never liked the feelings I got from it. Too much makes me sick and even a little gives me a headache.
I think that individual variation in brain chemistry and receptor density / locations, etc matters a LOT in that category. The trouble is... you just don't know what your chemistry is and what your brain is gonna like.
I know some people that don't like cocaine, it makes them feel jittery and uncomfortable at best. Some people take a hit of coke and it takes over their whole night and that's all they want to do for the rest of the night. I was never impressed.
Nictoine, arguably one of the most addictive substances ever, has always been one of my least favorite substances (to the point of being substantially less preferable than abstaining) despite constant exposure to it in my 20's from my friends. I never liked the feelings I got from it. Too much makes me sick and even a little gives me a headache.
I think that individual variation in brain chemistry and receptor density / locations, etc matters a LOT in that category. The trouble is... you just don't know what your chemistry is and what your brain is gonna like.