Rather, it was a reference to the fact that in the last few years, any time someone suggests that we might be in another tech bubble, there's always someone waiting to point out how "this time it's different", because now the web is mature and all the stupid startups are not really as stupid as they seem (not like in the first dot-com bubble).

Actually, it's a bit of a double entendre in that sense -- even the first dot-com bubble was rife with statements about how everything is different now, and we're in a "new economy" and all those "old economy" concepts like revenue and profit are totally obsolete. Plus ça change...